Dr. Sharma has held numerous government positions in India; working in the areas of agricultural development, food security, poverty alleviation, rural livelihood, natural resource management, gender, and financial management. She is former Secretary to the Govt of India, Ministry of Rural Development and former Secretary of the National Advisory Council of the Government of India. Dr. Sharma was instrumental in drafting the State and National Agriculture Policy, and in making policies that govern intellectual property management and commercialization of technologies in the Indian Council of Agricultural Research. She has represented India in the FAO, CGIAR, and the World Bank. She is a Hubert Humphrey Fellow and Chairperson of the Association of Indian Humphrey Fellows and is current Trustee of the World Agroforestry Centre and works on climate change issues.